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SSRI (Prosac, Cipramil, Seropram) Side Effects

Abstract: SSRIs can cause increased anxiety, sleeping problems, sexual problems, nausea, diarrhea. The SSRI side effects often disappear after a period of usage.

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SSRI (Prosac, Cipramil, Seropram) Side Effects

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Written by: , lecturer of Psychiatry in the University of Ioannina Medical School, Greece, Eva Gerasi, postgraduate student in the Department of Psychiatry, University Hospital of Ioannina, Greece and Jacob Palme, Professor, Stockholm University.
First version: 22 Jul 2008.
Latest revision: 29 Jul 2008.

What are the SSRI (Zoloft, Prosac, Fontex, Cipramil, Seropram, Fluoxetine, Paroxetin, Paxil, Remeron, Seroxat, Lexapro, Citalopram) side effects?


Side effects of selective serotonin re-uptake inhibitors include:
  • Nausea, loss of appetite, diarrhea.
  • Anxiety or irritability.
  • Problems sleeping or drowsiness.
  • Loss of sexual desire or ability. More.
  • Headaches or dizziness.
  • Weight gain. More.
They generally improve after a few days. People may tolerate SSRIs better than TCAs. They all lack sedation and are free of anticholinergic effects. This improves compliance but gives less immediate benefit for disturbed sleep (so they are initially combined with low doses of sedative antidepressants or hypnotics). All seem safe if overdosed.

There are many more side effects reported for SSRI drugs. For example, hair loss does occur, but not very often. The hair comes back when you stop using the drug, and switching to another SSRI drug sometimes helps.

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