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Amitriptyline (Elavil/Saroten/Endep/Vanatrip) - Counteractions

Abstract: What other drugs will affect amitriptyline (Elavil/Saroten/Endep/Vanatrip)?

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Amitriptyline (Elavil/Saroten/Endep/Vanatrip) - Counteractions

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Written by: , lecturer of Psychiatry in the University of Ioannina Medical School, Greece. Eva Gerasi, postgraduate student in the Department of Psychiatry, University Hospital of Ioannina, Greece.
First version: 22 Jul 2008.
Latest revision: 28 Jul 2008.

What other drugs will affect Amitriptyline (Elavil/Saroten/Endep/Vanatrip)?

Answer:

  • Amitriptyline should not be taken if the patient has taken a monoamine oxidase inhibitor such as Isocarboxazid (Marplan), Phenelzine (Nardil), or Tranylcypromine (Parnate) within the last 14 days.
  • Amitriptyline may increase the effects of other drugs that cause drowsiness, including other antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants.
  • Drugs other than those listed here may also interact with Amitriptyline. Therefore patients must first inform their doctor or pharmacist before taking any prescription or over-the-counter medicines, including herbal products.
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