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GABA (Gamma-Amiobutyric Acid)

Abstract: There is no study showing that GAB helps against depression, and since GABA does not pass the blood-brain barrier, it could not work.

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GABA (Gamma-Amiobutyric Acid)

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Question(s): 
Written by: Martin Winkler
First version: 22 Jul 2008.
Latest revision: 30 Jul 2008.

What is the effect of a supplement with GABA for depression?

Answer:

GABA = Gamma-Aminobutryic Acid is a neurotransmitter of the brain, which inhibits some relevant transmission of impulses within the cns-network. GABA is an amino-acid which is manufactured in the brain. But it cannot pass the blood-brain barrier. So any additional supplement to the food or pills will have no effect, because the drug won´t come to the place of action.

Many online-pharmacies try to promote the use of GABA to relief anxiety, depression or promote stimulation of growth hormones.

Any effect of this approach would be a placebo effect! There is no scientific evaluation of the use of GABA for these indication.

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